HighVista Strategies LLC (“HighVista”) is a private investment adviser founded in 2004 to design and make available investment strategies into which institutions and sophisticated investors can invest. HighVista is controlled by HighVista Management Partners LP, which is owned by HighVista Partners André Perold, Raphael Schorr, and other members of the HighVista management team. HighVista’s management team is responsible for managing firm operations, as well as formulating, implementing, and supervising HighVista’s investment strategy. HighVista provides investment advisory services to pooled investment vehicles (individually, a “Fund,” collectively, the “HighVista Funds”1), separately managed accounts (“Separate Account Clients”), and other clients (collectively hereinafter referred to as, “Clients”). HighVista utilizes a variety of investment strategies in the management of HighVista Client assets and, from time to time, launches additional strategies in response to the evolving needs of its business and its Clients. For HighVista’s Multi-Asset Strategy, HighVista: (i) evaluates a broad range of investments and asset classes; (ii) performs and utilizes proprietary research on risk and correlation behavior to optimize portfolio asset mix; and (iii) selects investments and manager partners in asset classes and strategies where potential benefit from active management is identified. HighVista creates multi- asset investment portfolios that allocate capital across both traditional investment assets (such as marketable domestic equity, international equity, and fixed income securities), and alternative assets (such as venture capital, private equity, and hedge funds), subject to portfolio restrictions. HighVista also manages Client assets that concentrate their investments in a single asset category or utilize a single component of HighVista’s Multi-Asset Strategy. HighVista provides investment advisory services to each of its Clients pursuant to investment management agreements (each, a “Management Agreement”) that direct HighVista to provide investment advice to the Client. In the case of the HighVista Funds, this direction is subject to the direction and control of any affiliated general partner or directors of the applicable HighVista Fund. In

the case of a collective investment trust, this direction is subject to the direction and control of the trustees of the trust. HighVista has sole and exclusive authority over the HighVista Funds’ direct investments into securities and other assets, including investments made through Subsidiary Funds, as well as the selection of third-party managers or investment vehicles if applicable (each, a “Third-Party Investment”), and makes decisions relating to the administration of the HighVista Funds. Except in specific circumstances agreed to by HighVista, investors in HighVista Funds generally cannot impose restrictions on the types of securities in which the applicable fund invests. The offer and sale of interests in the HighVista Funds is generally made to qualified purchasers through a confidential offering memorandum that is prepared for each such Fund and which provides information about the Fund’s objectives, strategies, risks, structure, costs, withdrawal terms and other matters of importance to investors. Additional information about HighVista’s business, history, organization and other matters addressed in this Item 4 can be found in the offering memorandum and governing documents of HighVista Funds. The information in this 1 Where applicable, the term “HighVista Funds” also includes wholly- or partially-owned holding companies or partnerships (each, a “Subsidiary Fund”), which are typically used to provide tax, operational, investment access or other benefits. The term also includes related separate accounts managed to facilitate investments by related pooled investment vehicles that are “HighVista Funds.” Brochure does not purport to be a complete description of HighVista Funds or each Funds respective investment strategy and is qualified in its entirety by each HighVista Fund’s offering, governing, and organizational documents (collectively, the “Governing Documents”). For Separate Account Clients and for other clients, a Management Agreement is entered into with each Client that summarizes the advisory services that will be provided by HighVista and addresses Client specific investment restrictions as well as strategies, risks, costs, and other matters of importance. As of December 31, 2022, HighVista’s regulatory assets under management was approximately $4,891,527,661, all of which is managed on a discretionary basis.